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Human Kallikrein

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产品名称: Human Kallikrein
产品型号: IHKa
产品展商: Innov-Research
产品文档: 无相关文档

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Human Kallikrein


Human Kallikrein  的详细介绍

Product Description

Human Kallikrein


Activation of Prekallikrein with Factor a-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

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