产品资料

HOPE® Fixative System II

如果您对该产品感兴趣的话,可以
产品名称: HOPE® Fixative System II
产品型号: 24824-1
产品展商: Polysciences
产品文档: 无相关文档

简单介绍

HOPE® Fixative System II


HOPE® Fixative System II  的详细介绍

HOPE® - Formalin-free fixation technique for molecular pathology and research!

Tissue conservation using the new HOPE®-technique provides paraffin embedded tissue blocks with native structure of the macro-molecules (protein, DNA, RNA) in the tissue.

During HOPE® fixation, tissue samples are incubated in HOPE® I solution, then in HOPE® II solution, followed by a dehydration with acetone and subsequent embedding in paraffin. For this tissue processing no alcohols or aldehydes (formalin, glutaraldehyde) are used. As a consequence, there is no cross-linking of macro- molecular structures during the process. This opens up new opportunities to characterize tissues out of paraffin blocks.

Applications for immunohistochemistry, in situ hybridization targeting RNA and DNA, PCR and RT-PCR have been demonstrated using properly prepared paraffin embedded tissue sections. Tissue specimens fixed with the HOPE® technique allow greater morphology and retrospective studies on the molecular level.

The HOPE®-Fixation technique requires HOPE® Fixative System II and HOPE® Fixative System I to complete the protocol.

Applications:

  • PCR
  • RT-PCR
  • Immunohistochemistry
  • In situ hybridization targeting RNA and DNA

Benefits:

  • Achieve IHC on paraffin tissue without antigen unmasking
  • IHC using antibodies which do not work on formalin fixed parafffin embedded tissue
  • No more overfixed formalin tissue samples
  • Unmatched results in RNA and DNA in situ hybridization
  • Excellent conservation of nucleic acids for PCR and RT-PCR

MSDS / Technical Data Sheets / Product Literature

产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

沪公网安备 31011202007337号