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System Bioscience
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System Biosciences (SBI) develops innovative research tools for Vectordelivery technologies, MicroRNA research, Exosome research, and GenomeEngineering tools, including the CRISPR-Cas9 SmartNuclease? system andPrecisionX? HR targeting vectors. Highlights: Vector Technologies: ? Powerfullentivector systems ? One-step transfection piggyBac transposons ? Single-copygene additions with phiC31 integrase vectors ? Sustained expression withoutintegration with Minicircle DNA plasmids Exosome Research Tools: ? Isolateexosomes with ExoQuick and ExoQuick-TC ? Exo-Flow- Immunopurify exosomes onmagentic beads and anlayze by FACS ? Culture cells in exosome-depleted FBS ?Verify exosome recovery with antibodies ? Quantitate exosomes with ELISAsGenome Engineering: ? RNA-guided Cas9 SmartNuclease system ? Fast and efficientmutation correction / gene editing ? HR donor vectors for knock-in, knock-out& tagging ? High-throughput, targeted integration with PinPoint technologyStem Cell Research: ? iPSC reprogramming systems ? Growth factors and media ?Pluripotency confirmation kits and antibodies ? iPS celllines, normal anddisease models ? Promoter lineage reporters in lentivectors Non-coding RNA: ?LncRNA qPCR profiling kits ? miRNome and OncoMir qPCR profiling systems ?Lenti-miR Precursor clone libraries – arrayed and pooled ? miRZip anti-miRclones for stable miRNA inhibition Exo-NGS Custom Service: ? Provide serum,tissue culture media, or other patient biofluids to SBI ? SBI isolatesexosomes, purifies RNA and generates high quality NGS libraries ? Sequencingperformed using Illumina MiSeq and HiSeq platforms ? Comprehensive dataanalysis, including generation of heat maps and top hits, provided ? NGS dataloaded onto a custom UCSC Genome Browser for convenient viewing.
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SBI 外泌体去除血清
Lentiviral Technology
ExpressionVectors
CumateInducible Vectors
TranscriptionReporter Vectors
VirusProduction
ReporterCell Lines
Genome Engineering
EZ-TALAssembly Kit
Cas9SmartNuclease
HRDonor Vectors
phiC31Integrase System
PinPointTargeting System
PiggyBacTransposon
MolecularTools
ColdFusion cloning
MetaMorphMutagenesis Kit
mRNAExpress RNA Synthesis Kit
PureFectiontransfection
Retrovirusconcentration
Cyto-Tracers
MolecularImaging Vectors
MycoQuick
MinicircleTechnology
Stem Cell Research
GrowthFactors and Media
iPSCReprogramming Systems
Antibodyand AP Staining Kits
iPS CellLines
PluripotencyReporters
TransdifferentiationFactors
MicroRNA Research
ExpressionProfiling
MicroRNAOverexpression
MicroRNAKnockdown
MicroRNAVirus Libraries
TargetSelection System
Discovery& Cloning
ExosomeResearch
ExosomeIsolation
ExosomeFACS
Exosome-depletedFBS
ExosomeDetection
SerummicroRNAs
LncRNAResearch
RNAi Libraries
ApplicationOverview
HumanGenome-wide
MouseGenome-wide
Pathway Focused
Gene Analysis
RNA-Quant cDNA Synthesis
FullSpectrum
MultiStartPrimers
InterferonResponse Detection Kit
ImmunologyResearch
Foxp3 vectors
RORyt vectors
T cellReporters
System Biosciences,简称SBI，美国加州湾区新成立的生技公司，致力于独特、**生物技术之开发，以研发利于基因及蛋白质功能鉴定、研究之崭新方法和工具为宗旨。 现阶段研发重心为RNA干扰（RNAi）研究之相关工具。 System Biosciences (SBI) 致力于开发独特、革新的技术，为客户研究蛋白组学和基因组学功能提供研究工具。SBI 是专业的慢病毒产品公司，提供基于慢病毒的所有相关产品、质粒、试剂盒及相关配套试剂和慢病毒延伸产品如IPS细胞多功能性诱导试剂盒和RNAi筛选文库。
System Biosciences热门产品：
外泌体去除血清 Exosome-depleted FBS Media Supplement 50ml SBI system 外泌体去除血清 外泌体去除血清 EXO-FBS-50A-1 Exosome-depleted FBS Media Supplement 50ml EXO-FBS-50A-1 SBI system Exosome-depleted FBS Media Supplement 50ml
Do you study bovine exosomes? If not, and you use fetal bovine serum (FBS) in your cell or tissue culture media, you may be isolating more bovine exosomes than you realize. Serum is a rich source of exosomes, FBS included. In order to help scientists study only the exosomes they want, SBI provides Exo-FBS? exosome-depleted FBS.
Standard growth media for most cells in culture require FBS as a growth supplement to DMEM. FBS is derived from bovine (cow) serum and contains a high abundance of cow exosome vesicles. These exosomes can interfere or cause significant background issues when studying the exosomes secreted from your cells of interest in standard culture conditions. SBI has developed an exosome-depleted FBS growth supplement called Exo-FBS that has been stripped of bovine exosomes. Exo-FBS supports equivalent growth of many types of cells in culture, is devoid of cow CD63-positive exosomes, and does not have any measurable bovine microRNAs. Cell growth in Exo-FBS is comparable to standard FBS. The process of manufacturing of Exo-FBS is a patented method in Patent No.: US 9,005,888 B2.
Perform your studies of cellular secreted exosomes in culture without the worry of contaminating cow exosomes in your experiments, and with no ultracentrifugation required when you use ExoQuick-TC. Available as standard FBS supplement or heat inactivated FBS media supplement (treated at 65°C for 15 minutes before bovine exosome removal).
System Biosciences SBI产品目录：
Cas9 SmartNuclease? Vectors. Simple genome editing using guide
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