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ABMgood
Anti-Myc (Ab-358) Antibody
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产品名称:
Anti-Myc (Ab-358) Antibody
产品型号:
产品展商:
ABM
产品文档:
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简单介绍
Anti-Myc (Ab-358)
Antibody
Anti-Myc (Ab-358) Antibody
的详细介绍
Overview
Print Version
Product Name
Anti-Myc (Ab-358)
Antibody
Description
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Subtype
polyclonal
Application
WB, IHC
Raised In
rabbit
Specificity
Myc (Ab-358) antibody detects endogenous levels of total Myc protein.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human Myc around the phosphorylation site of threonine 358 (R-R-TP-H-N).
Guarantee
abm
guarantees that all our Anti-Myc (Ab-358) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a
one-time replacement
at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Properties
Formulation
Liquid
Quantity
100 μg
Clone
N/A
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1µg/ul
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Species Reactivity
human, mouse, rat
Anti-Myc (Ab-358) Antibody Images
Specific References
Y021035 has been referenced in 1 publication.
Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182. Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.
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