产品资料

Nanog Adenovirus (Human)

如果您对该产品感兴趣的话,可以
产品名称: Nanog Adenovirus (Human)
产品型号:
产品展商: ABM
产品文档: 无相关文档

简单介绍

Nanog Adenovirus (Human)


Nanog Adenovirus (Human)  的详细介绍
Print Version
Vector pAdeno
Promoter CMV
Insert Nanog
Picture
Organism Human
Accession # Q9H9S0
Protein Type Wild Type
Protein Family Belongs to the Nanog homeobox family.
Functions Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation. The product can be used in combination with other iPSC factor for the induction of iPSC reprogramming.
Cell Types Expressed in fetal gonads, ovary and testis.
Protein Location Nucleus
Tag N-term His
Purification By Ion-Exchange column.
Quality Control By sequencing and Western blot analysis of transgene expression in transduced cells. Functional test includes iPSC reprogramming.
Titer >1x106pfu/mL
Storage 10 mM Tris-HCl, pH 8.0
Shipping High titer adenoviruses are shipped with dry ice and low titer adenoviruses are shipped with ice packs. For long term storage, it is recommended to store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles.
Notes There are 8 more vials in Box 24 Row E.
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

沪公网安备 31011202007337号