KLF4 Purified Protein

点击看大图

如果您对该产品感兴趣的话,可以

产品名称: KLF4 Purified Protein

产品型号:

产品展商: ABM

产品文档: 无相关文档

简单介绍

KLF4 Purified Protein

KLF4 Purified Protein 的详细介绍

	Print Version
Organism	Human
Accession #	O43474
Alias	EZF, GKLF
Protein Type	Wild Type
Protein Sequence	HHHHHHRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPGRPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESVAATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQVPPLHYQELMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHFESGGGGSPGRRRRRRRRR
Protein Family	Belongs to the krueppel C2H2-type zinc-finger protein family.
Functions	Transcription factor which acts as both an activator and repressor. KLF4 binds the CACCC core sequence. It also binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. KLF4 is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. KLF4 is one of the four factors in the Yamanaka protocol for iPSC reprogramming. The purified recombinant protein has a 6X His tag at N-terminus for purification and 9X poly-arginine at C-terminus for cell membrane penetration.
Cell Types	Unknown
Protein Location	Nucleus
Tag	6X His tag at N-terminus and 9X Poly-Arginine at C-terminus
Form	Liquid
Expression System	E.coli
Type	Purified Protein
Purification	Affinity Chromatography
Quality Control	By Western Blot Analysis
Concentration	250ug/ml
Storage	PBS
Shipping	On dry ice.
Notes	For Research Use Only, not for therapeutic or diagnostic purposes.
References	Induction of pluripotent stem cells from *** human fibroblasts by defined factors. Takahashi et al. Cell. 2007 Nov 30;131(5):861-72. Induction of pluripotent stem cells from mouse embryonic and *** fibroblast cultures by defined factors. Takahaski and Yamanaka. Cell. 2006 Aug 25;126(4):663-76. Epub 2006 Aug 10.

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!