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Recombinant Human CXCL11

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产品名称: Recombinant Human CXCL11
产品型号: Z100589
产品展商: ABM
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Recombinant Human CXCL11


Recombinant Human CXCL11  的详细介绍
Print Version
Alternative Names CXCL11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11
Recombinant Human IFN-Inducible T-cell Chemoattractant (CXCL11)
Description The CXCL11 belongs to the CXC chemokine family characterized by the presence of one amino acid in between the two NH2-terminal cysteines. CXCL11 is produced by a variety of cells including leukocytes, fibroblasts, and endothelial cells upon stimulation with interferons (IFNs). Simultaneous stimulation of fibroblasts or endothelial cells with IFN-gamma and Interleukin-1b or the TLR3 ligand double-stranded RNA results in a synergistic increase of CXCL11 production. CXCL11 attracts natural killer cells and activated T-helper 1 cells. Like CXCL9 and CXCL10, CXCL11 signals through CXC chemokine receptor 3 (CXCR3).
Gene Symbol CXCL11
Gene ID 6373
Accession No. O14625
Source E. coli
Appearance Lyophilized Powder
Molecular Weight 8.0 kDa
Endotoxin Level <1.0 EU/μg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Gel Image Click To Enlarge
Bioactivity Determined by its ability to chemoattract human T cells using a concentration range of 2.0-10.0 ng/mL
Bioactivity Data Click To Enlarge
Formulation Lyophilized from a 0.2 μm filtered solution in PB,100 mM NaCl pH 7.5
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
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