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Recombinant Mouse IL25

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产品名称: Recombinant Mouse IL25
产品型号: Z200259
产品展商: ABM
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Recombinant Mouse IL25


Recombinant Mouse IL25  的详细介绍
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Alternative Names UPF0556 protein, IL-25, Stromal cell-derived growth factor SF20, D17Wsu104e, Il25
Recombinant Mouse Interleukin-25 (IL25)
Description IL-25 (also known as IL- 17E), a member of the IL-17 family, has been implicated in Th2 cell-mediated immunity. Recently, IL-25 has been identified as one of the initiators of the Th2 response (10, 11) and has also been shown to be expressed by mast cells. The transgenic overexpression of IL-25 by lung epithelial cells results in mucus hyperproduction and airway infiltration of macrophages and eosinophils; conversely, IL-25 blockade reduced airway inflammation and Th2 cytokine production in an allergen-induced asthma model.
Gene Symbol IL25
Gene ID 140806
Accession No. Q9CPT4
Source E. coli
Appearance Lyophilized Powder
Molecular Weight 16.0 kDa
Endotoxin Level <1.0 EU/μg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Gel Image Click To Enlarge
Bioactivity The ED(50) was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was found to be <0.5ng/mL.
Bioactivity Data Click To Enlarge
Formulation Lyophilized from 0.2μm filtered solution in Tris and NaCl
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
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