Recombinant Human B-cell Maturation Protein (TNFRSF17)

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产品名称: Recombinant Human B-cell Maturation Protein (TNFRSF17)

产品型号: Z101445

产品展商: ABM

产品文档: 无相关文档

简单介绍

Recombinant Human B-cell Maturation Protein (TNFRSF17)

Recombinant Human B-cell Maturation Protein (TNFRSF17) 的详细介绍

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Alternative Names	Tumor necrosis factor receptor superfamily member 17, TNFRSF17, B cell maturation antigen, BCM, BCMA, CD269
Description	BCMA (B cell maturation) is a nonglycosylated integral membrane type I protein that is preferentially expressed in mature B lymphocytes.The N-terminal part of both mouse and human proteins contains a conserved six-cysteine motif. BLyS binds to three receptors of the TNF receptor family (B cell maturation antigen BCMA, TACI, and BAFF-R), all of which are expressed by mature B cells.
Gene Symbol	TNFRSF17
Gene ID	608
Accession No.	Q02223
Source	E. coli
Appearance	Lyophilized Powder
Molecular Weight	6.0 kDa
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity	>95% as determined by SDS-PAGE
Gel Image
Bioactivity	The ED(50) was determined by the dose-dependent proliferation of KMS15 cells and was found to be <0.05ng/mL.
Bioactivity Data
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS
Reconstitution	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage	For research use only. Not for diagnostic or therapeutic use.

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