Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody

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产品名称: Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody

产品型号: Y050566

产品展商: ABM

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Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody

Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody 的详细介绍

Overview	Print Version
Product Name	Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody
Description	GRB7(Growth factor receptor-bound protein 7) is a potential signal transduction molecule, and a variant of human Grb7 which is associated with invasive esophageal carcinoma. GRB7 interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. GRB7 also binds to ERBB2 and interacts with RND1. GRB7 belongs to the GRB7/10/14 family and contains 1 PH domain, 1 Ras-associating domain and 1 SH2 domain.
Subtype	polyclonal
Application	WB, ELISA
Raised In	rabbit
Immunogen	Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human Growth factor receptor-bound protein 7 (GRB7 adapter protein) or Epidermal growth factor receptor GRB-7 (B47).
Guarantee	abm guarantees that all our Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Properties
Formulation	Liquid
Quantity	100 μg
Clone	Polyclonal
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer	PBS, pH 7.4 with 0.05% sodium azide.
Concentration	1µg/ul
Purity	Purified by antigen-specific affinity chromatography.
Isotype	IgG
Species Reactivity	human
Specific References
Y050566 has been referenced in 1 publication. Kishi,T., et al, Biochem. Biophys. Res. Commun. 232 (1), 5-9 (1997) Tanaka,S., et al, J. Clin. Invest. 102 (4), 821-827 (1998) Tanaka,S., et al, Cancer Res. 57 (1), 28-31 (1997) Vayssiere,B., et al, FEBS Lett. 467 (1), 91-96 (2000)

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