Anti-Epidermal Growth Factor (EGF) Antibody

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产品名称: Anti-Epidermal Growth Factor (EGF) Antibody

产品型号: Y102556

产品展商: ABM

产品文档: 无相关文档

简单介绍

Anti-Epidermal Growth Factor (EGF) Antibody

Anti-Epidermal Growth Factor (EGF) Antibody 的详细介绍

Overview	Print Version
Product Name	Anti-Epidermal Growth Factor (EGF) Antibody
Description	Epidermal growth factor (EGF) has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide. EGF exerts its actions by binding to the EGFR, a 170 kDa protein. Epidermal growth factor (EGF) is a key growth factor regulating cell survival. Through its binding to cell surface receptors, EGF activates an extensive network of signal transduction pathways that include activation of the PI3K/AKT, RAS/ERK and JAK/STAT pathways. Because of its key role in driving the proliferation of cells, EGFR is a target of several anti-cancer drugs currently in development. Clone#: M01102818
Subtype	monoclonal
Application	Other
Raised In	mouse
Specificity	Specific for human EGF
Immunogen	Highly pure human epidermal growth factor
Guarantee	abm guarantees that all our Anti-Epidermal Growth Factor (EGF) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Properties
Formulation	Liquid
Quantity	500 μg
Clone	Monoclonal Antibody
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer	PBS, pH 7.3 with 0.1% sodium azide.
Purity	Affinity purified
Isotype	IgG1
Species Reactivity	human
Specific References
Y102556 has not yet been referenced specifically in any publications.

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