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ABMgood
Anti-Epidural Growth Factor (EGF), Human -BIOTIN Antibody
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产品名称:
Anti-Epidural Growth Factor (EGF), Human -BIOTIN Antibody
产品型号:
Y107129
产品展商:
ABM
产品文档:
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简单介绍
Anti-Epidural Growth Factor (EGF), Human -BIOTIN
Antibody
Anti-Epidural Growth Factor (EGF), Human -BIOTIN Antibody
的详细介绍
Overview
Print Version
Product Name
Anti-Epidural Growth Factor (EGF), Human -BIOTIN
Antibody
Description
Epidermal growth factor (EGF) has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide. EGF exerts its actions by binding to the EGFR, a 170 kDa protein. Epidermal growth factor (EGF) is a key growth factor regulating cell survival. Through its binding to cell surface receptors, EGF activates an extensive network of signal transduction pathways that include activation of the PI3K/AKT, RAS/ERK and JAK/STAT pathways. Because of its key role in driving the proliferation of cells, EGFR is a target of several anti-cancer drugs currently in development.
Subtype
polyclonal
Application
WB, ELISA
Raised In
rabbit
Immunogen
Produced from a sera of rabbits pre- immunized with highly pure(>98%) recombinant hEGF.
Guarantee
abm
guarantees that all our Anti-Epidural Growth Factor (EGF), Human -BIOTIN Antibody will perform as described on this product webpage, if this is not the case we will provide you with a
one-time replacement
at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Properties
Formulation
Liquid
Quantity
50 μg
Clone
Conjugated Polyclonal Antibody
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer
PBS solution containing 0.1% BSA
Purity
Affinity purified
Species Reactivity
human
Specific References
Y107129
has not yet been referenced specifically in any publications.
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