Biacore

Biacore公司 Biacore代理 Biacore**代理 Biacore中国代理

Label-free interaction analysis is of increasing importance for scientists in the academic, pharmaceutical, biotechnology and diagnostic markets. Setting the performance benchmark, Biacore systems generate unique data on the interactions between proteins and other molecules, including small molecule drug candidates. During research, development and manufacture, these data give insights into protein functionality, elucidate disease mechanisms and play a key role in the critical decisions needed for efficient development and production of therapeutics.

Biacore systems are used in areas such as pharmaceutical drug discovery, antibody characterization, proteomics, immunogenicity, biotherapeutic development and manufacture, and many life science research applications. A range of systems meet specific application needs. Customers include leading research centers, all of the leading global pharmaceutical companies, and many biotechnology companies.

In the food analysis market, a system and ready-to-use kits provide key manufacturers with the ability to determine quality and safety in areas such as quantification of vitamin content.

BIACORE是基于表面等离子共振（surface Plasmon resonance, SPR）开发的新型生物分析传感技术。该技术的3个核心部分是传感器芯片，SPR光学检测系统和微射流卡盘。实验时，现将一种生物分子固定在传感器的葡聚糖表面，将与之相互作用的分子溶于溶液流过的芯片表面。SPR检测器能根据跟踪溶液中的分子与芯片表面的分子结合、解离整个过程的变化，记录成一张传感图，并提供动力学和亲和力数据。BIACORE技术由于具有无需标记，高灵敏度，检测快速，并能实时定量测试等优势，已广泛用来研究蛋白质、核酸、多肽、小分子化合物等生物分子的相互作用。

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