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Virginiamycin B

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产品名称: Virginiamycin B
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简单介绍

CAS:3131-03-1Formula:C45H54N8O10MW:867Appearance:WhitesolidPurity:>99%byHPLC


Virginiamycin B  的详细介绍
*Please inquire the availability for this product. Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a synergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by several groups, leading to considerable confusion in the literature. Virginiamycin B acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

Additional Information

SynonymsOstreogrycin B, Pristinamycin IA, Streptogramin B, Syncothrecin B1, Synergistin B, Vernamycin Balpha, Virginiamycin 1A, NSC 125176, 14725-1, PA 114B, RP 12535
Product #V-2499
CAS #3131-03-1
Chemical NameN-((22S)-22-[4-(DIMETHYLAMINO)BENZYL]-6-ETHYL-10,23-DIMETHYL-5,8,12,15,17,21,24-HEPTAOXO-13-PHENYLDOCOSAHYDRO-12H-PYRIDO[2,1-F]PYRROLO[2,1-L][1,4,7,10,13,16]OXAPENTAAZACYCLONONADECIN-9-YL)-3-HYDROXY-2 -PYRIDINECARBOXAMIDE
FormulaC45H54N8O10
MW867
AppearanceWhite solid
Purity>99% by HPLC
SolubilitySoluble in ethanol, methanol, DMF, and DMSO,Limited water solubility
Storage Temp-20

Additional Information

InChIInChI=1S/C45H54N8O10/c1-6-31-42(59)52-22-11-14-32(52)43(60)51(5)34(24-27-16-18-29(19-17-27)50(3)4)44(61)53-23-20-30(54)25-33(53)39(56)49-37(28-12-8-7-9-13-28)45(62)63-26(2)36(40(57)47-31)48-41(58)38-35(55)15-10-21-46-38/h7-10,12-13,15-19,21,26,31-34,36-37,55H,6,11,14,20,22-25H2,1-5H3,(H,47,57)(H,48,58)(H,49,56)/t26?,31?,32?,33?,34-,36?,37?/m0/s1
SMILESCCC1C(=O)N2CCCC2C(=O)N([C@H](C(=O)N3CCC(=O)CC3C(=O)NC(C(=O)OC(C(C(=O)N1)NC(=O)c4c(cccn4)O)C)c5ccccc5)Cc6ccc(cc6)N(C)C)C
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