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Troglitazone

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产品名称: Troglitazone
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简单介绍

CAS:97322-87-7Formula:C24H27NO5SMW:441.54Appearance:Off-WhiteSolidPurity:95%byHPLC


Troglitazone  的详细介绍
An antidiabetic thiazolidinedione (TDZ) drug with anti-inflammatory and anti-tumor activities. A potent and selective PPAR agonist. The ECvalues for transactivation of human and murine PPAR in a cell-based assay are 0.55 and 0.78 M, respectively.

Additional Information

Synonyms5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione
Product #T-2469
CAS #97322-87-7
Chemical Name(±)-5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione
FormulaC24H27NO5S
MW441.54
AppearanceOff-White Solid
Purity95% by HPLC
SolubilityDMSO (25 mg/ml) or Ethanol (25 mg/ml)
Melting Point184-186 °C
Storage Temp-20°C
Therapeutic AreaEndocrinological Disorders
UseA potent and selective PPAR agonist.An antidiabetic thiazolidinedione (TDZ) drug with anti-inflammatory and anti-tumor activities

Additional Information

MDL NumberMFCD00878416
ChemACXX1065643-4
InChIInChI=1S/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,19,26H,9-12H2,1-4H3,(H,25,27,28)
SMILESCc1c(c2c(c(c1O)C)CCC(O2)(C)COc3ccc(cc3)CC4C(=O)NC(=O)S4)C
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