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Sulfo-Cyanine5.5 amine

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产品名称: Sulfo-Cyanine5.5 amine
产品型号: 173C0 273C0 473C0 573C0 673C0
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Sulfo-Cyanine5.5 amine 173C0 273C0 473C0 573C0 673C0


Sulfo-Cyanine5.5 amine  的详细介绍

Sulfo-Cyanine5.5 amine

Amines sulfo-Cyanine5.5
Cat. # Quantity Price Lead time
173C0 1 mg  $110.00 in stock
 
273C0 5 mg  $290.00 5 days
 
473C0 25 mg  $690.00 in stock
 
573C0 50 mg  $1190.00 in stock
 
673C0 100 mg  $1850.00 in stock
 
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Sulfo-Cyanine5.5 is a water soluble cyanine dye for far red / NIR applications such as in vivo imaging. The dye possesses four sulfonate groups that render it highly hydrophilic and water soluble. As well as other cyanines, sulfo-Cyanine5.5 has an outstanding extinction coefficient that makes it a bright fluorescent label for the far red region.

This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. The aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc), and also be used in enzymatic transamination labeling.

Sulfo-Cyanine5.5 amine
Sulfo-Cyanine5.5 amine
Sulfo-Cyanine5.5 amine
Structure of sulfo-Cyanine5.5 amine
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Absorption and emission spectra of sulfo-Cyanine5.5 fluorophore

Absorption and emission spectra of sulfo-Cyanine5.5 fluorophore

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A water soluble near infrared emitting dye for in vivo imaging applications. Sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield, and containing a linker arm.
 

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Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.
 

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Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.
 

General properties

Appearance: dark blue solid
Molecular weight: 1077.41
Molecular formula: C46H54K2N4O13S4
IUPAC name: (E)-4-[(2E,4E)-5-{5-[6-(6-Aminohexylamino)-6-oxohexyl]-3,3-dimethyl-10,12-bis(oxysulfonyl)-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentadienylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonic acid dipotassium salt
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download

Spectral properties

Excitation maximum, nm: 673
ε, L?mol?1?cm?1: 195000
Emission maximum, nm: 691
CF260: 0.09
CF280: 0.11

Product citations

  1. Malinovskaya, Y.; Melnikov, P.; Baklaushev, V.; Gabashvili, A.; Osipova, N.; Mantrov, S.; Ermolenko, Y.; Maksimenko, O.; Gorshkova, M.; Balabanyan, V.; Kreuter, J.; Gelperina, S. Delivery of doxorubicin-loaded PLGA nanoparticles into U87 human glioblastoma cells. International Journal of Pharmaceutics2017, 524(1–2), 77–90. doi: 10.1016/j.ijpharm.2017.03.049
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